摘要 |
<p>PROBLEM TO BE SOLVED: To provide a method for industrial preparation of an optically active lysine derivative which is useful as an intermediate of medicines. SOLUTION: After protecting an amino group or the amino group together with a carboxyl group of optically active 2-amino-6-methyl-6-nitroheptanoic acid with a protecting group, the nitro group is reduced to synthesize a 6, 6- dimethyl-lysine derivative. Then, the 6, 6-dimethyl-lysine derivative is reacted with an acetic acid derivative.</p> |