ANTISENSE MODULATION OF TRANSFORMING GROWTH FACTOR BETA RECEPTOR II EXPRESSION
摘要
Antisense compounds, compositions and methods are provided for modulating the expression of Transforming growth factor beta receptor II. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Transforming growth factor beta receptor II. Methods of using these compounds for modulation of Transforming growth factor beta receptor II expression and for treatment of diseases associated with expression of Transforming growth factor beta receptor II are provided.
申请公布号
WO03000656(A2)
申请公布日期
2003.01.03
申请号
WO2002US19665
申请日期
2002.06.19
申请人
ISIS PHARMACEUTICALS, INC.;MURRAY, SUSAN, F.;WYATT, JACQUELINE, R.