发明名称 Human collagenase inhibitor, recombinant vector system for using same and recombinant DNA method for the manufacture of same
摘要 A portable DNA sequence is disclosed which is capable of directing intracellular production of metalloproteinanse inhibitors. Vectors containing this portable DNA sequence are also set forth, including the vector pUC9-F5/237P10 (ATCC Accession No. 53003). A recombinant-DNA method for the microbial production of a metalloproteinase inhibitor, which method incorporates at least one of the portable DNA sequences and the vectors disclosed herein.
申请公布号 US2003003556(A1) 申请公布日期 2003.01.02
申请号 US20010987357 申请日期 2001.11.14
申请人 AMGEN INC. 发明人 CARMICHAEL DAVID F.;ANDERSON DAVID C.;STRICKLIN GEORGE P.;WELGUS HOWARD G.
分类号 C12N9/99;A61K38/00;A61P43/00;C07H21/04;C07K14/00;C07K14/24;C07K14/245;C07K14/81;C12N9/64;C12N15/00;C12N15/09;C12N15/62;C12N15/70;C12P21/00;C12P21/02;C12R1/125;C12R1/19;C12R1/385;C12R1/865;C12R1/91;(IPC1-7):C12N9/99;C12N5/06 主分类号 C12N9/99
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