发明名称 Process for the preparation of polyether phosphates
摘要 The invention provides an improved process for the synthesis of compounds carrying at least one phosphate group, especially polyalkylene glycol phosphate compounds, said process comprising the steps of: (a) reacting a compound containing at least one primary alcohol moiety with a diaryl- or diaralkyl-halophosphate whereby to form the corresponding diaryl- or diaralkyl-phosphate ester; (b) reductively cleaving the resulting product; and (c) if desired, repeating steps (a) and (b) with the product of step (b) whereby to produce a compound carrying two or more phosphate groups. Advantages of the process in accordance with the invention are that this avoids the production of by-products and results in products which are low in impurities. Also provided are novel diaryl- and diaralkyl-phosphate ester compounds, in particular polyethylene glycol diphenylphosphate ester and derivatives thereof.
申请公布号 US6500917(B1) 申请公布日期 2002.12.31
申请号 US20000489831 申请日期 2000.01.24
申请人 AMERSHAM HEALTH AS 发明人 SAINDANE MANOHAR TUKARAM;LADD DAVID LEE
分类号 C07F9/09;C08G65/322;C08G65/335;(IPC1-7):C08G79/02;C07F9/02 主分类号 C07F9/09
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