Production method of alpha-methylene-gamma-butyrolactones

摘要

The present invention relates to a method for producing an alpha-methylene-gamma-butyrolactone which is one of basic structures often shown in drugs such as an anti-cancer agent by reacting an alene compound having an aldehyde or ketone group with carbon monoxide via cyclization in a single step in the presence of a catalyst containing ruthenium, thereby improving total yield of the entire reaction and achieving effects of cost reduction.