| 摘要 |
<p>FIELD: medicine, applicable for electric pore forming therapy. SUBSTANCE: regression of tumors in vivo was caused with the use of electric pore forming therapy and a chemotherapeutic agent. In one variation of realization the method represents an electric pore forming therapy with the use of low voltage and high pulse wavelength for inducing of cell destruction. In one variation the device for clinical electric pore forming has an electrode in the form of a group of needles, which determines the preset value of voltage of the treatment pulse. A number of constructions of the electrode applicator provides for an access and treatment of various tissue areas. The other version of realization represents a laparoscopic needle applicator, which is preferably combined with an endoscope for minimum invasive electric pore forming therapy. EFFECT: enhanced purging of the cell at delivery of pharmaceutic compounds and genes. 68 cl, 17 dwg, 8 tbl, 4 ex</p> |
