Bicyclic amino acids as pharmaceutical agents

摘要

The compounds of the disclosed are bicyclic amino acids and their pharmaceutically acceptable salts, and the prodrugs of the amino acids which are useful in the treatment of epilepsy, faintness attacks, hypokinesia, cranial disorders, neurodegenerative disorders, depression, anxiety, panic, pain, arthritis, neuropathological disorders, and sleep disorders. The compounds are those of formulae I, II, III and IV. Wherein n is an integer of/from 1 to 4, where there are stereocenters, each center may be independently R or S. Preferred compounds of the disclosed are those of Formulae I - IV wherein n is an integer of/from 2 to 4.