FLUOROUS TRIPHASE AND OTHER MULTIPHASE SYSTEMS

摘要

A method of reacting a first compound to produce a second compound includes the step of contacting a first non-fluorous phase including the first compou nd with a first fluorous phase at a first phase interface. The first compound distributes between the first fluorous phase and the first non-fluorous phas e. The method further includes the steps of contacting the first fluorous phase with a second non-fluorous phase at a second phase interface and including a t least a third compound in the second non-fluorous phase that reacts with the first compound to produce the second compound. The second compound has a distribution coefficient less than the first compound. This method can, for example be used to separate the second compound from unreacted first compoun d wherein, for example, the first compound is of a fluorous nature and distributes more readily into (or transports more quickly through) the fluorous phase than does the second compound. In general, the fluorous phase serves as a barrier to prevent the two non-fluorous phases from mixing, but molecules that can migrate through the fluorous phase can pass from one side to the other.