发明名称 Use of MHC class II ligands as adjuvant for vaccination and of LAG-3 in cancer treatment
摘要 The present invention concerns a use of a MHC class II ligand, such as CD4 and LAG-3. for the manufacture of a medicament for preventing or treating pathological conditions involving an antigen specific immune response, as well as the use of LAG-3 in cancer-immunotherapy. The invention also concerns a pharmaceutical composition comprising an effective amount of an antigen able to induce an antigen-specific immune response together with an effective amount of a MHC class II ligand wherein said MHC class II ligand is present as an adjuvant-like agent.
申请公布号 US2002192195(A1) 申请公布日期 2002.12.19
申请号 US20020041600 申请日期 2002.01.10
申请人 INSTITUT GUSTAVE ROUSSY 发明人 TRIEBEL FREDERIC
分类号 A61K48/00;A61K38/00;A61K38/17;A61K39/00;A61K39/39;A61M36/14;A61P31/04;A61P31/12;A61P33/10;A61P35/00;A61P37/02;C12N5/08;C12N5/10;C12N15/63;(IPC1-7):A61K48/00;C12N15/87 主分类号 A61K48/00
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