发明名称 1,2,4-triazolo[4,3-B]pyrido[3,2-D]pyridazine derivatives and pharmaceutical compositions containing them
摘要 Heterocyclic compounds of formula (I), wherein R1 represents a hydrogen atom or a -(CH2)M-Y group, wherein m is an integer from 0 to 4 and Y represents an alkyl, haloalkyl, alkoxy, alkoxycarbonyl, C3-C7 cycloalkyl, norbornyl or phenylalkenyl group, or an aromatic group which aromatic group^may optionally be substituted by one or more halogen atoms; R2 represents an aromatic group which aromatic group may optionally be substituted by one or more halogen atoms or alkyl, alkoxy, C3-C6 cycloalkoxy, methylenedioxy, nitro, dialkylamino or trifluoromethyl groups, and R3 represents a hydrogen or halogen atom or an alkyl group, and pharmaceutically acceptable salts thereof, processes for preparing the same. The compounds are phosphodiesterase 4 inhibitors.
申请公布号 US2002183326(A1) 申请公布日期 2002.12.05
申请号 US20020038777 申请日期 2002.01.08
申请人 ALMIRALL PRODESFARMA, S.A. 发明人 FERRER JORDI GRACIA;CRESPO CRESPO M. ISABEL;VEGA NOVEROLA ARMANDO;FERNANDEZ GARCIA ANDRES
分类号 C07D487/04;A61K31/50;A61K31/5025;A61P1/00;A61P11/06;A61P17/00;A61P27/14;A61P29/00;A61P37/08;C07D221/00;C07D237/00;C07D249/00;C07D471/14;(IPC1-7):A61K31/502;C07D487/14 主分类号 C07D487/04
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