METHODS FOR PROTECTING ALLOGENEIC ISLET TRANSPLANT USING SOLUBLE CTLA4 MUTANT MOLECULES
摘要
The present invention is a method of inhibiting islet cell transplant rejection paricular, to treat diabetes, such as type-1 and type-2 diabetes, by administering to a subject an effective amount of a soluble CTLA4 mutant molecule. One example of soluble CTLA4 mutant molecule is L104EA29YIg.
申请公布号
WO02094202(A2)
申请公布日期
2002.11.28
申请号
WO2002US16708
申请日期
2002.05.23
申请人
EMORY UNIVERSITY;LARSEN, CHRISTIAN, P.;PEARSON, THOMAS, C.;ADAMS, ANDREW, B.
发明人
LARSEN, CHRISTIAN, P.;PEARSON, THOMAS, C.;ADAMS, ANDREW, B.