Catalyst system, useful for enantioselective reduction of ketones to form chiral alcohols, comprises oxazaborolidine compound on Raney nickel, cobalt or iron

摘要

Catalyst system comprises an oxazaborolidine fixed to Raney nickel, cobalt or iron is used in the preparation of chiral alcohols by reduction of prochiral ketones with a boron-based reducing agent. Independent claims are also included for; (1) Preparation of the catalyst; and (2) Enantioselective reduction process using the above catalyst.