摘要 |
<p>The present invention provides a method for the generation and identification of cell lines that posses genetically unstable genes. More specifically, the present invention provides a method for detecting genes associated in genetic alterations by using specific genes capable of inducing genetic instability such as metastasin 1 gene and their protein product. The products expressed by cells identified as possessing unstable genes are used as therapeutics or therapeutic targets.</p> |