| 发明名称 |
ADENO-ASSOCIATED VIRUSES AND USES THEREOF |
| 摘要 |
The invention provides an isolated and purified DNA molecule comprising at least one DNA segment, a biologically active subunit or variant thereof, of a circular intermediate of adeno-associated virus, which DNA segment confers increased episomal stability, persistence or abundance of the isolated DNA molecule in a host cell. The invention also provides a composition comprising at least two adeno-associated virus vectors.
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| 申请公布号 |
WO0125465(A9) |
申请公布日期 |
2002.11.21 |
| 申请号 |
WO2000US27863 |
申请日期 |
2000.10.06 |
| 申请人 |
UNIVERSITY OF IOWA RESEARCH FOUNDATION;ENGELHARDT, JOHN, F.;DUAN, DONGSHENG;YAN, ZIYANG |
发明人 |
ENGELHARDT, JOHN, F.;DUAN, DONGSHENG;YAN, ZIYANG |
| 分类号 |
C12N15/09;A61K35/76;A61K38/00;A61K48/00;A61P43/00;C12N5/10;C12N7/01;C12N15/864;(IPC1-7):C12N15/864 |
主分类号 |
C12N15/09 |
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