CANCER REMEDY COMPRISING ANTHRANILIC ACID DERIVATIVE AS ACTIVE INGREDIENT

摘要

A cancer remedy comprising a compound represented by the following formula as an active ingredient: <CHEM> wherein, X represents a group represented by either of the following formulae: <CHEM> wherein, R<1> and R<2> represent each a hydrogen atom, a hydroxy group, a trihalomethyl group, a C1-C12 alkoxy group or alkylthio group, a (substituted) C7-C11 aralkyloxy group or a (substituted) C3-C10 alkenyloxy group; R<4> and R<5> represent each a hydrogen atom, a halogen atom, a C1-C4 alkyl group or a C1-C4 alkoxy group; A represents -O-, -S-, -S(=O)-, -S(=O)2-, -CH2-, -OCH2-, -SCH2, -C(=O)- or -CH(OR<6>)-; Y represents a hydrogen atom, a halogen atom, a nitro group, a nitrile group, an amino group, -COOR<7>, -NHCOR<8> or -NHSO2R<9>; E represents -C(=O)-, -CR<10>R<11>C(=O)-, -CH2CH2C(=O)- or -CH=CHC(=O)-; G represents a hydrogen atom, a hydroxy group, -SO2NH2, -COOR<3>, -CN or a tetrazol-5-yl group; and Z represents a hydrogen atom, a halogen atom, a nitro group or a methyl group.