摘要 |
Disclosed are phthalimido compounds of the formula: (see formula I) (wherein R4 is aryl, heteroaryl or cycloalkyl; R3 is hydrogen, cycloalkyl, alkyl or phenyl; R6 is hydrogen, alkyl, cycloalkyl, aryl, heteroaryl, phenyl-alkyl, benzhydryl or benzyl; and C8H4O2N- represents phthalimido) useful as intermediate for producing cyclic ethylenediamine derivatives of the formula : (see formula II) (wherein R1 is hydrogen, alkyl or the like; R2 is hydrogen, benzyl or the like; R5 is hydrogen, alkyl or the like and the other symbols are as defined above) that are substance P antagonists useful as medicine.</ SDOAB>
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