发明名称 |
NUCLEIC ACID VACCINE COMPRISING A FUSION PROTEIN INCLUDING AN ADJUVANT SEQUENCE FROM A PLANT VIRAL COAT PROTEIN |
摘要 |
A nucleic acid construct is provided for delivery into living cells in vivo for inducing an immune response in a patient to an antigen; the construct directing the expression of a fusion protein, said fusion protein comprising said antigen and an adjuvant sequence derived from a plant viral coat protein. Methods for making such constructs, and methods of using such constructs for the treatment of infectious disease, cancer and B cell malignancy, are provided. |
申请公布号 |
WO0240513(A3) |
申请公布日期 |
2002.11.07 |
申请号 |
WO2001GB05142 |
申请日期 |
2001.11.20 |
申请人 |
CANCER RESEARCH VENTURES LIMITED;SAVELYEVA, NATALIA;STEVENSON, FREDA |
发明人 |
SAVELYEVA, NATALIA;STEVENSON, FREDA |
分类号 |
A61K39/00;A61K39/385;C07K14/08 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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