发明名称 1,4,5,6-TETRAHYDROPYRAZOLO-[3,4-C]-PYRIDIN-7-ONES AS FACTOR XA INHIBITORS
摘要 <p>The present application describes 1,4,5,6-tetrahydropyrazolo-[3,4-c]-pyridin-7-ones of Formula (I) or pharmaceutically acceptable salt forms thereof, wherein ring R is 3-amido or 4-methoxy, R1 is trifluoromethyl or amido, and R2 is aminomethyl, N-methylaminomethyl, and N,N-dimethylaminomethyl. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.</p>
申请公布号 WO2002085353(A1) 申请公布日期 2002.10.31
申请号 US2002012204 申请日期 2002.04.17
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