发明名称 |
MHC-ANTIGEN COMPLEXES FOR DETECTING AND PURIFYING ANTIGEN-SPECIFIC T CELLS |
摘要 |
T cells are specifically labeled according to their antigen receptor by binding of a multimeric binding complex. The complex is prepared with major histocompatibility complex protein subunits having a homogeneous population of peptides bound in the antigen presentation site. The multimeric MHC-antigen complex forms a stable structure with T cells, thereby allowing for the labeling, identification and separation of specific T cells.
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申请公布号 |
CA2212747(C) |
申请公布日期 |
2002.10.29 |
申请号 |
CA19962212747 |
申请日期 |
1996.02.27 |
申请人 |
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY |
发明人 |
MCHEYZER-WILLIAMS, MICHAEL G.;DAVIS, MARK M.;ALTMAN, JOHN D. |
分类号 |
G01N33/53;A61K38/00;C07K14/725;C07K14/74;C12N9/00;C12N15/09;C12P21/02;G01N33/569;(IPC1-7):C07K19/00;C12Q1/24;G01N33/532;G01N33/566 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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