发明名称 |
TROPANE ALKALOID MULTIDRUG RESISTANCE INHIBITORS FROM ERYTHROXYLUM PERVILLEI AND USE OF THE SAME |
摘要 |
Compounds and methods of modulating the activity of P-glycoproteins are disclosed. The method utilizes compounds derived from Erythroxylum pervillei . the compounds overcome multidrug resistance and can be used therapeutically to enhance performance of therapeutic drugs, like chemotherapeutic drug and antibiotics.
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申请公布号 |
CA2443655(A1) |
申请公布日期 |
2002.10.24 |
申请号 |
CA20022443655 |
申请日期 |
2002.04.11 |
申请人 |
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS |
发明人 |
KINGHORN, A. DOUGLAS;PEZZUTO, JOHN M. |
分类号 |
A61K31/46;A61K45/00;A61P31/04;A61P35/00;A61P43/00;C07D451/12;(IPC1-7):C07D451/12 |
主分类号 |
A61K31/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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