| 发明名称 |
Non-steroidal estrogen receptor ligands |
| 摘要 |
Novel non-steroidal estrogen receptor ligands and methods of synthesis are disclosed. The novel molecules are intended for use in therapeutic preparations for the treatment of estrogen receptor related disease states. The compounds specified are tetra-cyclic derivatives and have been shown to be antiproliferative against human estrogen-dependent cancer cells and to have good binding affinity for the estrogen receptor.
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| 申请公布号 |
US2002156077(A1) |
申请公布日期 |
2002.10.24 |
| 申请号 |
US20010934254 |
申请日期 |
2001.08.21 |
| 申请人 |
SCHMIDT JONATHAN MARTIN;MERCURE JULIE;LOWELL JEFFRY LAWRENCE;KWIATKOWSKI STEFAN;PUPEK KRZYSZTOF;ZHU SHUGUANG;WHELAN JOHN;LAZAROWYCH NATALIE |
发明人 |
SCHMIDT JONATHAN MARTIN;MERCURE JULIE;LOWELL JEFFRY LAWRENCE;KWIATKOWSKI STEFAN;PUPEK KRZYSZTOF;ZHU SHUGUANG;WHELAN JOHN;LAZAROWYCH NATALIE |
| 分类号 |
A61P35/00;C07D295/092;C07D311/80;(IPC1-7):C07D335/08;C07D413/02;C0749/02 |
主分类号 |
A61P35/00 |
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