THE USE OF BETA 1,3 - GLUCAN - CONTAINING COMPOSITIONS TO POTENTIATE IMMUNE RESPONSES BY UPREGULATING THE EXPRESSION OF COSTIMULATORY MOLECULES
摘要
An improved method and immunopharmacological composition for upregulating the expression of the co-stimulatory molecule B7 is provided. A beta 1,3-glucan-containing composition is provided that can upregulate the cell surface expression of B7 molecules on antigen presenting cells like macrophages, thereby allowing these antigen presenting cells to more effectively initiate adaptive immune responses to foreign antigens like pathogenic microorganisms and tumors.
申请公布号
WO02083061(A2)
申请公布日期
2002.10.24
申请号
WO2001US43711
申请日期
2001.11.06
申请人
IMMUSONIC, INC.;HUNTER, KENNETH, W.;GAULT, RUTH, A.;JORDAN, FRANK, M.
发明人
HUNTER, KENNETH, W.;GAULT, RUTH, A.;JORDAN, FRANK, M.