摘要 |
<p>Heterocycle derivatives of general formula (1) or salts thereof, being useful as drugs, wherein A is heteroaryl or an oxide thereof; B is ethenylene; D is optionally substituted phenylene; and E is a group of general formula (2) [wherein G is optionally substituted phenyl; and R is heteroaryl, heteroarylmethyl, or a group of general formula (3), (wherein n is an integer of 1 to 5; and R5 and R6 are each independently hydrogen, C1 6 alkyl, hydroxyalkyl, or aminoalkyl, or alternatively R5 and R6 together with the nitrogen atom adjacent thereto (i.e., NR5R6) may represent a five to seven membered cycloamino group)].</p> |