| 摘要 |
<p>The invention concerns a composite molecular system for use in restitutive chemotherapy against viral infection,, the sys- tem being obtained as follows: (l) preparing lignin units high in polysaccharides (PLP) by: extraction, in weakly acid or alkaline conditions, from wood or wood-like materials and/or from plant-cell cultures (A) in aqueous media; separating off the insoluble solids; (II) preparing low-molecular-weight lignoid units low in polysaccharides (LPL) by: alkaline-aqueous extraction (p11 7-14) from wood-carbonization products or bio-converted wood-like materials (B); separating off the alkali-insoluble solids; (lll) pre- paration of a water-soluble mixed polymer [LD(PLP=LPL)] by: reacting the product of step (I), the lignin units high in polysac- charides (PLP), with the products of step (II) the lignoid units low in polysaccharides (LPL), in alkaline aqueous conditions (pH 9.12, isolating the LD fractions of this HD(PLP = LPL) mixed polymer by ultr a- filtration, taking the cut between the nominal values of about 15 and 40 kD and discarding the residue; treating the soluti on with an H+ Cation-exchange agent at pH 3 to 7.0 and processing the acid LD(LPL = PLP) system. This system can be used in particular as a parenterally or locally applied system against viral infections, including retroviruses, in particular those of the HIV type, as well as AIDS viruses,</p> |
