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发明名称 SULPHONES WHICH MODULATE THE ACTION OF GAMMA SECRETASE
摘要 Novel sulphones of Formula I are disclosed: wherein A completes a 4-7 member ed ring optionally comprising up to two heteroatoms. The compounds modulate the action of g-secretase and are therefore useful in the treatment or preventio n of Alzheimer's disease.
申请公布号 CA2442882(A1) 申请公布日期 2002.10.17
申请号 CA20012442882 申请日期 2001.08.21
申请人 MERCK SHARP & DOHME LIMITED 发明人 SHAW, DUNCAN EDWARD;NADIN, ALAN JOHN;OAKLEY, PAUL JOSEPH;OWENS, ANDREW PATE;CHURCHER, IAN;DINNELL, KEVIN;HARRISON, TIMOTHY;CASTRO PINEIRO, JOSE LUIS;KERRAD, SONIA;TEALL, MARTIN RICHARD;WILLIAMS, SUSANNAH;WILLIAMS, BRIAN JOHN
分类号 A61K31/045;A61K31/10;A61K31/122;A61K31/13;A61K31/133;A61K31/138;A61K31/15;A61K31/16;A61K31/166;A61K31/19;A61K31/197;A61K31/215;A61K31/27;A61K31/277;A61K31/341;A61K31/351;A61K31/357;A61K31/40;A61K31/4015;A61K31/41;A61K31/415;A61K31/4164;A61K31/4166;A61K31/4192;A61K31/4196;A61K31/421;A61K31/4245;A61K31/426;A61K31/433;A61K31/438;A61K31/4402;A61K31/4406;A61K31/4409;A61K31/4412;A61K31/445;A61K31/4453;A61K31/4468;A61K31/451;A61K31/495;A61K31/5375;A61K31/54;A61K31/695;A61P25/28;A61P43/00;C07C317/12;C07C317/14;C07C317/20;C07C317/24;C07C317/30;C07C317/44;C07C317/46;C07D207/12;C07D207/26;C07D207/27;C07D207/40;C07D207/404;C07D211/18;C07D211/42;C07D211/46;C07D211/54;C07D211/58;C07D211/60;C07D211/62;C07D213/36;C07D213/40;C07D213/64;C07D213/65;C07D231/12;C07D233/32;C07D233/34;C07D233/40;C07D233/54;C07D233/60;C07D233/61;C07D233/64;C07D233/72;C07D241/08;C07D241/18;C07D249/04;C07D249/08;C07D249/12;C07D257/04;C07D263/22;C07D263/38;C07D263/44;C07D271/06;C07D271/10;C07D277/26;C07D285/12;C07D295/08;C07D295/088;C07D295/096;C07D295/14;C07D295/18;C07D295/182;C07D307/52;C07D309/08;C07D309/10;C07D317/46;C07D317/48;C07D317/72;C07D491/10;C07D491/113;C07D491/20;C07D521/00;C07F7/08;(IPC1-7):C07C317/46;C07D241/06;C07D217/20;C07D207/24;C07D309/28;C07D211/72;C07D211/78 主分类号 A61K31/045
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