| 发明名称 |
MODULATION OF OLIGONUCLEOTIDE CpG-MEDIATED IMMUNE STIMULATION BY POSITIONAL MODIFICATION OF NUCLEOSIDES |
| 摘要 |
The invention provides methods for modulating the immune response caused by CpG-containing oligonucleotides. The methods according to the invention enable both decreasing the immunostimulatory effect for antisense applications, as well as increasing the immunostimulatory effect for immunotherapy applications.
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| 申请公布号 |
WO0155370(A9) |
申请公布日期 |
2002.10.17 |
| 申请号 |
WO2001US02681 |
申请日期 |
2001.01.26 |
| 申请人 |
HYBRIDON, INC. |
发明人 |
AGRAWAL, SUDHIR |
| 分类号 |
C12N15/09;A61K31/7088;A61K31/7125;A61K48/00;A61P37/04;C07H21/00;C12N15/117;(IPC1-7):C12N15/11;A61K31/712 |
主分类号 |
C12N15/09 |
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