发明名称 |
1,3-Disubstituted pyrrolidines, process of their preparation and pharmaceutical preparation in which they are comprised |
摘要 |
<p>The invention provides compounds of formula (I) wherein R<SUB>0</SUB>, R<SUB>1</SUB>, R<SUB>2 </SUB>and A are as defined in the description, and the preparation thereof. The compounds of formula (I) have high affinity as alpha<SUB>2 </SUB>adrenoceptors and hence are useful as pharmaceuticals.</p> |
申请公布号 |
CZ20022581(A3) |
申请公布日期 |
2002.10.16 |
申请号 |
CZ20020002581 |
申请日期 |
2001.01.26 |
申请人 |
NOVARTIS AG |
发明人 |
SEILER MAX PETER;NOZULAK JOACHIM |
分类号 |
A61K31/40;A61K31/4025;A61K31/424;A61K31/4439;A61K31/454;A61K31/498;A61P3/10;A61P15/10;A61P25/00;A61P25/02;A61P25/16;A61P25/18;A61P25/24;A61P25/28;A61P25/30;A61P27/06;A61P43/00;C07D207/08;C07D207/09;C07D401/06;C07D403/06;C07D405/06;C07D405/08;C07D405/12;C07D413/06;C07D417/06;(IPC1-7):C07D401/06;A61K31/402 |
主分类号 |
A61K31/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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