发明名称 |
Method for producing L-lysine |
摘要 |
A recombinant DNA autonomously replicable in cells of coryneform bacteria, comprising a DNA sequence coding for an aspartokinase in which feedback inhibition by L-lysine and L-threonine is substantially desensitized, and a DNA sequence coding for a diaminopimelate decarboxylase; a coryneform bacterium harboring an aspartokinase in which feedback inhibition by L-lysine and L-threonine is substantially desensitized, and comprising an enhanced DNA sequence coding for a diaminopimelate decarboxylase; and a method for producing L-lysine comprising the steps of cultivating the coryneform bacterium in an appropriate medium to allow L-lysine to be produced and accumulated in a culture of the bacterium, and collecting L-lysine from the culture. |
申请公布号 |
EP0857784(A3) |
申请公布日期 |
2002.10.16 |
申请号 |
EP19970121444 |
申请日期 |
1997.12.05 |
申请人 |
AJINOMOTO CO., INC. |
发明人 |
HAYAKAWA, ATSUSHI;SUGIMOTO, MASAKAZU;YOSHIHARA, YASUHIKO;NAKAMATSU, TSUYOSHI |
分类号 |
C12N15/09;C07H21/04;C12N1/21;C12N9/12;C12N9/88;C12N15/00;C12N15/54;C12N15/60;C12P13/08;C12R1/15 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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