发明名称 BENZOFURAN DERIVATIVES
摘要 The invention relates to substituted benzofuran derivatives, a method for the production thereof and the use of the same as pharmaceuticals for treating Alzheimer's disease, cardiovascular diseases and diabetes. The effectiveness of the compounds is associated with decreasing serum cholesterol. Said derivatives correspond to formula (I) wherein Z represents O, S, SO, SO2, CH2, CHF, CF2 or NR8; R8 represents hydrogen or (C1-C4) alkyl; R5 and the two carbon atoms of the phenyl ring form a saturated or unsaturated furan ring which is optionally identically or differently substituted once or twice; R7 represents hydrogen or a cation or a group, preferably such as alkyl or acetyl, which can be split under physiological conditions during the formation of an OH function.
申请公布号 CA2442265(A1) 申请公布日期 2002.10.10
申请号 CA20022442265 申请日期 2002.03.25
申请人 BAYER AKTIENGESELLSCHAFT 发明人 BISCHOFF, HILMAR;JONGHAUS, WILHELM;FAESTE, CHRISTIANE;VOEHRINGER, VERENA;REINEMER, PETER;KRETSCHMER, AXEL;SCHMECK, CARSTEN;MUELLER, ULRICH;HAUSWALD, MARKUS;SCHMIDT, DELF;ZOCHE, MARTIN;SCHMIDT, GUNTER;PERNERSTORFER, JOSEF;APELER, HEINER;HANING, HELMUT
分类号 A61P7/00;C07D307/80;C07D307/84;C07D307/85;(IPC1-7):C07D307/78;A61K31/343;C07D307/87 主分类号 A61P7/00
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