Methods of determining the likelihood of the re-occurrence of tumors and of determining the aggressiveness of post-surgical treatment are provided which rely on analysis of a loss of heterogeneity at the particular chromosomal locus 3p24.3. Loss of expression or hypermethylation of the thyroid hormone receptor beta 1 gene is also predictive of an increased re-occurrence of tumors.
申请公布号
WO02076286(A2)
申请公布日期
2002.10.03
申请号
WO2002US09068
申请日期
2002.03.20
申请人
CALIFORNIA PACIFIC MEDICAL CENTER;DAIRKEE, SHANAZ, H.;LI, ZHENG