| 发明名称 |
USE OF IKK- beta INHIBITORS AND METHOD FOR DISCOVERY OF SAID INHIBITORS |
| 摘要 |
The invention relates to the use of an IKK-ss inhibitor for the production of a medicament for the treatment or prevention of atheroscleroses. A screening method for the discovery of IKK-ss inhibitors in endothelial cells is also disclosed. The method involves the contacting of a potential inhibitor with activated endothelial cells and a determination of the secretion of MCP-1 from the endothelial cells. |
| 申请公布号 |
WO02076482(A2) |
申请公布日期 |
2002.10.03 |
| 申请号 |
WO2002EP03382 |
申请日期 |
2002.03.26 |
| 申请人 |
PROCORDE GMBH;UNGERER, MARTIN;BRAND, KORBINIAN;GAWAZ, MEINRAD |
发明人 |
UNGERER, MARTIN;BRAND, KORBINIAN;GAWAZ, MEINRAD |
| 分类号 |
G01N33/50;A61K31/7088;A61K38/00;A61K38/46;A61K39/395;A61K45/00;A61K48/00;A61P9/10;A61P43/00;C07K14/47;C12Q1/02;G01N33/15;G01N33/53;G01N33/566 |
主分类号 |
G01N33/50 |
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