发明名称 |
Process for making amlodipine, derivatives therof, and precursors therefor |
摘要 |
Amlodipine and related analogues thereof are prepared by the following general reaction scheme: R1 and R2 each independently represent a C1-C4 alkyl group. The process provides for the formation of compounds of formula (1) in good yield and purity. Further, the compounds of formula (1) can be used as calcium channel blockers or as reference standards or reference markers for checking the purity of amlodipine.
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申请公布号 |
US2002143046(A1) |
申请公布日期 |
2002.10.03 |
申请号 |
US20010938840 |
申请日期 |
2001.08.27 |
申请人 |
PETERS THEODORUS H. A.;BENNEKER FRANCISCUS B. G.;SLANINA PAVEL;BARTL JIRI |
发明人 |
PETERS THEODORUS H. A.;BENNEKER FRANCISCUS B. G.;SLANINA PAVEL;BARTL JIRI |
分类号 |
A61K9/20;A61K9/48;A61K31/44;C07D209/48;C07D211/90;C07D401/12;(IPC1-7):A61K31/403;C0729/48 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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