| 摘要 |
PROBLEM TO BE SOLVED: To provide a ruthenium compound, its diamine ligand and a method for the highly stereospecific production of an optically active alcohol in high yield by using the ruthenium compound as a catalyst. SOLUTION: The ruthenium compound is expressed by Ru(X)(Y)(Px)n1 [R<1> R<2> C*(NR<3> R<4> (-A-R<5> R<6> C*(NR<7> R<8> )] [X and Y are each independently H, a halogen atom, carboxy, hydroxy or a 1-20C alkoxy; Px is phosphine ligand; R<1> to R<8> are each independently H, a (substituted) 1-20C alkyl or the like; A is a 1-3C alkylene which may contain substituents and ether bond or the like; the mark (*) represents an asymmetric carbon atom; and n1 is 1 or 2], the diamine compound is expressed by R<1> R<2> C*(NR<3> R<4> )-A-R<5> R<6> C*S(NR<7> R<8> ) and the method for the production of the optically active alcohol comprises the asymmetric reduction of a condensed-ring ketone or an α-aminoketone with hydrogen in the presence of the ruthenium compound. |
