DISEASE ASSOCIATED POLYMORPHISM IN THE CTLA-4 LOCUS

摘要

The present invention relates to the identification of Single Nucleotide Polymorphisms (SNPs) and haplotypes in the CTLA-4 locus and their association with a predisposition, susceptibility or resistance to autoimmune disease such as Graves Disease (GD) or Type 1 Diabetes Mellitus.(T1DM)