发明名称 |
Pablo, a polypeptide that interacts with Bcl-xL, and uses related thereto |
摘要 |
The present invention relates, at least in part, to polypeptides which include Bcl-xL binding domains, novel Bcl-xL binding domains of Pablo polypeptides, nucleic acid molecules encoding such polypeptides, and uses thereof. For example, such polypeptides and nucleic acid molecules are useful in modulating apoptosis, particularly in neural cells, as well as in the treatment or prevention of disorders that can benefit from modulation of cell death.
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申请公布号 |
US2002137049(A1) |
申请公布日期 |
2002.09.26 |
申请号 |
US20010858155 |
申请日期 |
2001.05.15 |
申请人 |
AMERICAN HOME PRODUCTS CORPORATION |
发明人 |
MARK ROBERT;YOUNG KATHLEEN H.;WOOD ANDREW |
分类号 |
A01K67/027;A61K38/00;A61K45/00;A61K48/00;A61P21/02;A61P25/00;A61P25/16;A61P25/28;A61P43/00;C07K14/47;C07K19/00;C12N5/08;C12N5/10;C12N15/09;C12N15/12;C12Q1/02;G01N33/15;G01N33/50;G01N33/53;G01N33/566;(IPC1-7):C12Q1/68;C07H21/04;C12N9/64;C12P21/02;C12N5/06 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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