| 发明名称 |
Neurotoxins with enhanced target specificity |
| 摘要 |
Modified neurotoxins that contain protease cleavage sites susceptible uniquely to proteases present in certain tissues are described. The toxins can be selectively activated by proteases in muscle or selectively inactivated by proteases in blood.
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| 申请公布号 |
US2002137886(A1) |
申请公布日期 |
2002.09.26 |
| 申请号 |
US20000726949 |
申请日期 |
2000.11.29 |
| 申请人 |
LIN WEI-JEN;AOKI KEI ROGER;STEWARD LANCE E. |
发明人 |
LIN WEI-JEN;AOKI KEI ROGER;STEWARD LANCE E. |
| 分类号 |
C12N15/09;A61K38/00;C07K14/33;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12P21/02;(IPC1-7):C07K14/24;C07H21/04 |
主分类号 |
C12N15/09 |
| 代理机构 |
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代理人 |
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