发明名称 |
Amidine derivatives which are inhibitors of nitric oxide synthase |
摘要 |
There are provided novel compounds of formula (I) wherein R1, R2, X, Y and Z are as defined in the Specification and optical isomers, racemates and tautomers thereof and pharmaceutically acceptable salts thereof; tocether with processes for their preparation, compositions containing them and their use in therapy. The compounds are inhibitors of the enzyme nitric oxide synthase.
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申请公布号 |
US2002137750(A1) |
申请公布日期 |
2002.09.26 |
申请号 |
US20010763838 |
申请日期 |
2001.02.27 |
申请人 |
DEBORAH D.W. CHEN;EMPFIELD JAMES R.;MACDONALD JAMES E.;MATTES KENNETH C.;MURRAY ROBERT;PHILLIPS EIFION;SCHMITTHENNER HANS |
发明人 |
DEBORAH D.W. CHEN;EMPFIELD JAMES R.;MACDONALD JAMES E.;MATTES KENNETH C.;MURRAY ROBERT;PHILLIPS EIFION;SCHMITTHENNER HANS |
分类号 |
A61P9/00;A61P9/10;A61P25/06;A61P25/16;A61P25/18;A61P25/28;A61P29/00;C07D307/68;C07D333/38;C07D409/12;(IPC1-7):C0749/02;A61K31/496;A61K31/452;A61K31/402;A61K31/381 |
主分类号 |
A61P9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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