发明名称 |
PROCESS FOR FOLDING CHEMICALLY SYNTHESIZED POLYPEPTIDES |
摘要 |
The present invention relates to a process for folding chemically synthesized polypeptides, comprising treating a polypeptide and/or protein that comprises two or more derivatized cysteine residues with a reducing agent in a folding buffer having a predetermined pH and temperature, wherein the derivatized cysteine residue corresponds to S-butyl-thio-cysteine residue and wherein the reducing agent is cysteine. |
申请公布号 |
WO0250099(A3) |
申请公布日期 |
2002.09.19 |
申请号 |
WO2001EP14163 |
申请日期 |
2001.11.27 |
申请人 |
RMF DICTAGENE S.A.;VERDINI, ANTONIO;CORRADIN, GIAMPIETRO;ROGGERO, MARIO |
发明人 |
VERDINI, ANTONIO;CORRADIN, GIAMPIETRO;ROGGERO, MARIO |
分类号 |
C07K1/04;C07K1/113;C07K1/14 |
主分类号 |
C07K1/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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