Disclosed are molecules that activate an RXR receptor, wherein the molecule comprises an RXR binding portion which binds the RXR receptor and comprise a side pocket contacting residue which contacts a side-pocket 1 of an RXR receptor.
申请公布号
CA2473156(A1)
申请公布日期
2002.09.19
申请号
CA20022473156
申请日期
2002.03.08
申请人
INCYTE SAN DIEGO INCORPORATED
发明人
PLEYNET, DAVID P. M.;GUO, JIANHUA;JAKUBOWICZ-JAILLARDON, KARINE;FINE, RICHARD;AL-SHAMMA, HUSSIEN A.;FANJUL, ANDREA;SPRUCE, LYLE W.;PFAHL, MAGNUS;TACHDJIAN, CATHERINE;ZAPF, JAMES W.
