发明名称 |
IMPROVEMENTS IN OR RELATING TO IMMUNE RESPONSES TO HIV |
摘要 |
Disclosed is an immunogen in sterile form suitable for administration to a human subject, the immunogen comprising: at least a portion of the gag protein of HIV, said gag protein being from an HIV clade or having a consensus sequence for one or more HIV clades, and comprising at least parts of p17 and p24; and a synthetic polypeptide comprising a plurality of amino acid sequences, each sequence comprising a human CTL epitope of an HIV protein, and wherein a plurality of HIV proteins are represented in the synthetic polypeptide, said CTL epitopes being selected to stimulate an immune response to one or more HIV clades of interest. |
申请公布号 |
EP1240186(A2) |
申请公布日期 |
2002.09.18 |
申请号 |
EP20000985690 |
申请日期 |
2000.12.22 |
申请人 |
MEDICAL RESEARCH COUNCIL;INTERNATIONAL AIDS VACCINE INITIATIVE;UNIVERSITY OF NAIROBI |
发明人 |
HANKE, TOMAS;MCMICHAEL, ANDREW JAMES |
分类号 |
C12N15/09;A61K38/00;A61K39/00;A61K39/02;A61K39/21;A61K48/00;A61P31/18;C07K14/155;C07K14/16;C12N1/21;C12N7/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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