Azithromycin preparation in its noncryst alline and crystalline dihydrate forms

摘要

The present invention describes new procedures for the preparation of the macrolide azithromycin in its non-crystalline and crystalline dihydrate forms, which are characterized and clearly differentiated by means of the following methods and techniques:1. IR Spectroscopy.2. Differential Scan Calorimetry (DSC).3. X-Ray Diffraction.4. Hygroscopicity.5. Crystallinity test (Light Polarized Microscopy)