发明名称 COMPOSITIONS AND PREPARATIONS OF SILYMARIN COMPLEX WITH THE IMPROVED BIOAVAILABILITY
摘要 <p>Disclosed is a novel composition and manufacturing method of silymarin complex with enhanced bioavailability which is applied for the prevention and treatment of liver diseases and a method of preparing therefor. The composition of the invention is prepared by adding tromethamine and poloxamer 407 in certain amounts which promote the absorption of water-insoluble silymarin in the digestive tract, thereby improving water solubility and enhancing bioavailability thereof.</p>
申请公布号 WO2002069962(A1) 申请公布日期 2002.09.12
申请号 KR2002000291 申请日期 2002.02.25
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