| 发明名称 |
Solid dosage forms of divalproex sodium |
| 摘要 |
The present invention is directed to an aqueous process for granulating valproate compounds, in which the pH of the granulation solution is maintained at a pH of 5 or below. The invention is also directed to dosage forms in which the residual content of organic solvents is reduced to a level of 0.2 w/w % or less.
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| 申请公布号 |
US2002127277(A1) |
申请公布日期 |
2002.09.12 |
| 申请号 |
US20000748659 |
申请日期 |
2000.12.22 |
| 申请人 |
QIU YIHONG;ENGH KEVIN R.;FAITSCH LYNN;SLADE RUSSELL T. |
发明人 |
QIU YIHONG;ENGH KEVIN R.;FAITSCH LYNN;SLADE RUSSELL T. |
| 分类号 |
A61K9/16;A61K9/20;A61K9/54;A61K31/19;(IPC1-7):A61K9/54;A61K9/14 |
主分类号 |
A61K9/16 |
| 代理机构 |
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