POLYNUCLEOTIDES, POLYPEPTIDES, REMEDIES FOR CANCER AND VACCINES

摘要

The present invention provides polynucleotides, polypeptides, remedies for cancer, and vaccines, which are used for diagnosing autoimmune diseases such as graft-versus-host disease, and graft-versus-leukemia, and treating and preventing acute or chronic myeloid leukemia. The polynucleotides includes a base sequence that is identical or substantially identical with a base sequence represented by SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7, SEQ ID NO: 8, SEQ ID NO: 9, and SEQ ID NO: 10. The polypeptide includes an amino acid sequence that is identical or substantially identical with an amino acid sequence encoded by the above-mentioned polynucleotide. The remedy for cancer contains the polynucleotides or polypeptides, and strengthens the defense mechanism in a living body to thereby treat cancer. The vaccine contains the polynucleotides or polypeptides, and makes living bodies to acquire the defense mechanism to thereby prevent the onset of cancer.