发明名称 |
Pyrazine and triazine derivatives of 1,2,4,5-tetrahydro-Benzo or Thieno [d] azepine |
摘要 |
The invention relates to compounds which are represented by the formula wherein R1, R2, R3, R4, X and Y are as defined in the specification, as well as pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing these compounds and to a process for their preparation. The compounds possess affinity towards metabotropic glutamate receptors and are therefore useful in the treatment or prevention of acute and/or chronic neurological disorders.
|
申请公布号 |
US2002123488(A1) |
申请公布日期 |
2002.09.05 |
申请号 |
US20010020680 |
申请日期 |
2001.12.12 |
申请人 |
BINGGELI ALFRED;MAERKI HANS-PETER;MUTEL VINCENT;WILHELM MAURICE;WOSTL WOLFGANG |
发明人 |
BINGGELI ALFRED;MAERKI HANS-PETER;MUTEL VINCENT;WILHELM MAURICE;WOSTL WOLFGANG |
分类号 |
A61K31/495;A61K31/53;A61K31/55;A61P1/08;A61P9/10;A61P13/02;A61P19/00;A61P21/00;A61P21/04;A61P25/00;A61P25/04;A61P25/06;A61P25/08;A61P25/14;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P25/36;A61P27/02;A61P43/00;C07D403/04;C07D495/04;(IPC1-7):A61K31/55;C0743/04;C07D223/16 |
主分类号 |
A61K31/495 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|