发明名称 |
Novel compounds capable of modulating biofilms |
摘要 |
The invention features a novel method for identifying compounds capable of affecting a microbial biological activity, such as biofilm formation, development and dissolution. The method includes: (a) obtaining supernatant from a closed culture system that contains at least one type of microorganism; (b) exposing a target organism to the supernatant or an extract thereof; and (c) measuring the level of the biological activity. Compounds identified by this method are provided, as wells as methods for disrupting biofilms and inhibiting or promoting their formation.
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申请公布号 |
US2002123077(A1) |
申请公布日期 |
2002.09.05 |
申请号 |
US20010966826 |
申请日期 |
2001.09.28 |
申请人 |
O'TOOLE GEORGE A.;KOLTER ROBERTO;DAVEY MARY ELLEN;BLANK DAVID H.;CAIAZZA NICKY C.;HOGAN DEBORAH A. |
发明人 |
O'TOOLE GEORGE A.;KOLTER ROBERTO;DAVEY MARY ELLEN;BLANK DAVID H.;CAIAZZA NICKY C.;HOGAN DEBORAH A. |
分类号 |
C12Q1/02;C12Q1/18;(IPC1-7):G01N33/53;C07K1/00;C07K14/00;C07K17/00;G01N33/567 |
主分类号 |
C12Q1/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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