Solid dispersion containing sialic acid derivative

摘要

The invention provides a medicament comprising a sialic acid derivative represented by the following formula and have superior solubility and absorbability. A solid dispersion comprising a water-soluble macromolecule such as hvdroxypropylmethylcellulose and a sialic acid derivative dispersed in the water-soluble macromolecule and represented by the following formula (I):[R1 represents a steroid compound residue; R2 represents hydrogen atom or a C1-C4 alkyl group, R3 represents a C1-C15 alkyl group etc.; X represents an oxygen atom or a sulfur atom], e.g., 3alpha-[N-(5-acetamido-3,5-dideoxy-2-O-methyl-alpha-D-glycero-D-galacto-2-noneuropyranosonyl)amino]cholestane.