发明名称 Conjugates and methods of forming conjugates of oligonucleotides and carbohydrates
摘要 Oligonucleotides conjugated to carbohydrates and methods for their production are described. These oligonucleotide-carbohydrate conjugates are resistant to degradation by nucleases, are able to form stable duplexes with RNA, and have utility as inhibitors of gene expression.
申请公布号 US6444806(B1) 申请公布日期 2002.09.03
申请号 US19970837651 申请日期 1997.04.22
申请人 HISAMITSU PHARMACEUTICAL CO., INC. 发明人 VEERAPANANI DANGE;NOZAWA IWAO
分类号 C12N15/09;A61K31/70;A61K48/00;C07H21/00;C07H21/04;C12N15/113;C12P19/34;(IPC1-7):C07H21/00;A01N43/04;G01N33/566 主分类号 C12N15/09
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