发明名称 DRUG DELIVERY DEVICES
摘要 1. Pressurised dispensing container for dispensing a medicament, wherein at least a portion of one or more of the internal surfaces of components of the pressurised dispensing container which come into contact with medicament during storage or dispensing has a layer of one or more cold plasma polymerised monomers bonded to at least a portion thereof, wherein said layer is of a cold plasma polymerised fluorinated hydrocarbon. 2. Pressurised dispensing container as claimed in claim 1 in which the one or more monomers for cold plasma polymerisation are selected from the group of materials comprising perfluoro-cyclohexane, perfluoro-hexane, tetrafluoroetyhlene, trifluoroethylene, vinylidene, fluoride, vinylfluoride, fluoroethylene and fluoropropylene. 3. Metering valve for use with a pressurised dispensing container, the valve comprising a valve stem co-axially slidable within a valve member, said valve member and valve stem defining an annular metering chamber, outer and inner annular seals operative between the respective outer and inner ends of the valve member and the valve stem to seal the annular metering chamber therebetween, wherein at least a portion of an internal surface of the metering valve has a layer of one or more cold plasma polymerised monomers bonded thereto wherein the layer is of a cold plasma polymerised fluorinated hydrocarbon. 4. Metering valve as claimed in claim 3 in which said internal surface comprises a surface of the metering chamber. 5. Metering valve as claimed in either of claims 3 or 4 in which the internal surface comprises a surface of the valve member. 6. Metering valve as claimed in any one of claims 3 to 5 in which the internal surface comprises a surface of the valve stem. 7. Metering valve as claimed in any one of claims 3 to 6 in which the internal surface comprises a surface of either of both of said outer and inner annular seals. 8. Metering valve as claimed in any one of claims 3 to 7 in which the valve further comprises a valve body in which the valve member is located, the valve body having a layer of one or more cold plasma polymerised monomers bonded thereto, wherein the layer is of a cold plasma polymerised fluorinated hydrocarbon. 9. Metering valve as claimed in any one of claims 3 to 8 further comprising a gasket extending between the sealing surfaces of the metering valve and a pressurised dispensing container, said gasket having a layer of one or more cold plasma polymerised monomers bonded thereto, wherein the layer is of a cold plasma polymerised fluorinated hydrocarbon. 10. Metering valve substantially as hereinbefore described with reference to and as shown in the accompanying drawings.
申请公布号 EA002639(B1) 申请公布日期 2002.08.29
申请号 EA20000000866 申请日期 1999.02.19
申请人 GLAXO GROUP LIMITED 发明人 WARBY, RICHARD, JOHN
分类号 B65D83/34;A61M11/08;A61M15/00;B05B9/04;B05D5/08;B05D7/24;B65D83/14;B65D83/36;C08F2/52;C08F14/00;C08G61/02 主分类号 B65D83/34
代理机构 代理人
主权项
地址