摘要 |
<p>Molecules of the general formula (I) without intramolecular peptidic bonds, able to mimic the RGD peptide, containing ARG-GLY-ASP motif 'arginine-glycine-aspartic acid' (that is a potent inhibitor, in vivo and in vitro, of cellular adhesion). In vitro experimentation demonstrated that said molecules are efficient inhibitors of RASMC adhesion, proliferation and migration.</p> |